Studies of drugs given before anaesthesia. XVII: The natural and semi-synthetic opiates.

نویسندگان

  • W B Loan
  • J D Morrison
  • J W Dundee
  • R S Clarke
  • R C Hamilton
  • S S Brown
چکیده

The sedative and toxic properties of morphine, and five semi-synthetic opiates (diamorphine, dihydromorphinone, dihydrocodeine, oxymorphone and oxycodone) have been determined by giving them, in a double-blind trial, as pre-anaesthetic medication to a standard female population. Diamorphine and dihydromorphinone produced the best sedation whilst dihydrocodeine was least efficient in this respect. Dihydromorphinone and oxymorphone were markedly more toxic than the others, whilst dihydrocodeine was the least toxic drug in this group.

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عنوان ژورنال:
  • British journal of anaesthesia

دوره 41 1  شماره 

صفحات  -

تاریخ انتشار 1969